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Valproic acid

CAS No. 99-66-1

Valproic acid ( VPA;2-Propylpentanoic Acid )

产品货号. M16914 CAS No. 99-66-1

A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
1G ¥405 有现货

生物学信息

  • 产品名称
    Valproic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
  • 产品描述
    A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2; induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients; reduces tumor growth and metastasis formation in animal model.Migraine Approved
  • 同义词
    VPA;2-Propylpentanoic Acid
  • 通路
    Cell Cycle/DNA Damage
  • 靶点
    HDAC
  • 受体
    GABA; Sodium Channel; HDACs
  • 研究领域
    Neurological Disease
  • 适应症
    Migraine

化学信息

  • CAS Number
    99-66-1
  • 分子量
    144.21
  • 分子式
    C8H16O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in H2O
  • SMILES
    CCCC(CCC)C(O)=O
  • 化学全称
    Pentanoic acid, 2-propyl-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Krmer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.
2. Gttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
产品手册
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